Retatrutide 5mg
$119.00
Retatrutide is a GGG tri-agonist that targets GLP-1 and GIP receptors, akin to standard GLP-1 agonists, but also uniquely activates the glucagon receptor. This extra receptor interaction enhances glucagon production, leading to the breakdown of stored fats and glycogen, thereby increasing basal metabolism for more consistent fat loss. Its actions on GLP-1 and GIP receptors promote delayed gastric emptying and appetite control, offering a comprehensive approach to obesity research distinct from older GLP-1 agonists. Further research is required
What Is Retatrutide?
Retatrutide is an investigational peptide developed by Eli Lilly. It’s designed to mimic three key metabolic hormones:
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GLP-1 (glucagon-like peptide-1)
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GIP (glucose-dependent insulinotropic polypeptide)
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Glucagon
This makes it a triple agonist, meaning it activates three different hormone receptors that are involved in metabolism, appetite regulation, and fat burning.
What Does It Do?
In research and clinical studies, Retatrutide has shown:
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Dramatic weight loss effects (comparable or even superior to semaglutide and tirzepatide)
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Improved blood sugar control
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Enhanced insulin sensitivity
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Increased energy expenditure
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Fat loss with muscle preservation
How It Works
Retatrutide’s triple action targets multiple pathways:
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GLP-1: Reduces appetite, delays gastric emptying, and improves insulin response.
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GIP: Enhances insulin secretion and works synergistically with GLP-1.
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Glucagon: Increases energy expenditure and promotes fat burning.
Together, these create a metabolic trifecta—reducing calorie intake while increasing the number of calories burned.
Why the Hype?
In Phase 2 clinical trials, Retatrutide showed up to 24% body weight reduction over 48 weeks—that’s massive. Researchers believe it could become one of the most effective anti-obesity drugs on the horizon.
Still Experimental
Retatrutide is not FDA-approved and is strictly for research purposes at this stage. Human use is not allowed outside of clinical studies.

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